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Folding of Polypeptide Chains in Proteins: A Proposed Mechanism for Folding

A mechanism is proposed for the folding of protein chains. On the basis of short-range interactions, certain aminoacid sequences have a high propensity to be, say, α-helical. However, these short helical (or other ordered) regions can be stabilized only by long-range interactions arising from the pr...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Lewis, Peter N., Momany, Frank A., Scheraga, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1971
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389403/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2293
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