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Immature human thymocytes can be driven to differentiate into nonlymphoid lineages by cytokines from thymic epithelial cells.

The signals and cellular interactions required for hematopoietic stem-cell commitment to the T lineage are unknown, yet are central to understanding the early stages of normal T-cell development. To study the differentiative capacity of T-cell precursors, we isolated CD4-, CD8-, surface(s) CD3- thym...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Kurtzberg, J, Denning, S M, Nycum, L M, Singer, K H, Haynes, B F
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298108/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2678108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7575
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