Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes.

Thymocytes from DO10 T-cell-receptor transgenic mice undergo apoptosis, or programmed cell death, when chicken ovalbumin-(323-339) peptide is administered in vivo. Using DO10 mice thymocytes, we have now developed a simple in vitro model system that recapitulates the in vivo clonal-deletion process....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Iwabuchi, K, Nakayama, K, McCoy, R L, Wang, F, Nishimura, T, Habu, S, Murphy, K M, Loh, D Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9000
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