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Experimental Characterization and Mathematical Modeling of P2X7 Receptor Channel Gating
The P2X7 receptor is a trimeric channel with three binding sites for ATP, but how the occupancy of these sites affects gating is still not understood. Here we show that naive receptors activated and deactivated monophasically at low and biphasically at higher agonist concentrations. Both phases of r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980950/ https://ncbi.nlm.nih.gov/pubmed/20962242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2390-10.2010 |
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