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The P2X(7) Receptor Channel Pore Dilates under Physiological Ion Conditions

Activation of the purinergic P2X(7) receptor leads to the rapid opening of an integral ion channel that is permeable to small cations. This is followed by a gradual increase in permeability to fluorescent dyes by integrating the actions of the pannexin-1 channel. Here, we show that during the prolon...

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Hlavní autoři: Yan, Zonghe, Li, Shuo, Liang, Zhaodong, Tomić, Melanija, Stojilkovic, Stanko S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571973/
https://ncbi.nlm.nih.gov/pubmed/18852304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810059
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