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The P2X(7) Receptor Channel Pore Dilates under Physiological Ion Conditions

Activation of the purinergic P2X(7) receptor leads to the rapid opening of an integral ion channel that is permeable to small cations. This is followed by a gradual increase in permeability to fluorescent dyes by integrating the actions of the pannexin-1 channel. Here, we show that during the prolon...

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Detalhes bibliográficos
Main Authors: Yan, Zonghe, Li, Shuo, Liang, Zhaodong, Tomić, Melanija, Stojilkovic, Stanko S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571973/
https://ncbi.nlm.nih.gov/pubmed/18852304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810059
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