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Removing all obstacles: A critical role for p53 in promoting tissue renewal

Defects in DNA repair pathways or exposure to high levels of DNA damaging agents limit the renewal potential of adult tissues and accelerate the development of age-related degenerative pathologies.1–3 Many studies suggest these tissue homeostatic defects can result from the accumulation of DNA damag...

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Hlavní autoři: Schoppy, David W., Ruzankina, Yaroslava, Brown, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980577/
https://ncbi.nlm.nih.gov/pubmed/20234190
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