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Sorafenib inhibits cAMP-dependent ERK activation, cell proliferation, and in vitro cyst growth of human ADPKD cyst epithelial cells

In autosomal dominant polycystic kidney disease (ADPKD), aberrant proliferation of the renal epithelial cells is responsible for the formation of numerable fluid-filled cysts, massively enlarged kidneys, and progressive loss of renal function. cAMP agonists, including arginine vasopressin, accelerat...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamaguchi, Tamio, Reif, Gail A., Calvet, James P., Wallace, Darren P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980397/
https://ncbi.nlm.nih.gov/pubmed/20810616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00387.2010
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