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Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer’s and Parkinson’s diseases

Normal mitochondrial dynamics consist of fission and fusion events giving rise to new mitochondria, a process termed mitochondrial biogenesis. However, several neurodegenerative disorders manifest aberrant mitochondrial dynamics, resulting in morphological abnormalities often associated with deficit...

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Detalhes bibliográficos
Main Authors: Nakamura, Tomohiro, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978885/
https://ncbi.nlm.nih.gov/pubmed/20177970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-010-0476-x
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