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S-Nitrosylation of Critical Protein Thiols Mediates Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

Excessive nitrosative and oxidative stress is thought to trigger cellular signaling pathways leading to neurodegenerative conditions. Such redox dysregulation can result from many cellular events, including hyperactivation of the N-methyl-d-aspartate-type glutamate receptor, mitochondrial dysfunctio...

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Detalles Bibliográficos
Autores principales: Nakamura, Tomohiro, Lipton, Stuart A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061195/
https://ncbi.nlm.nih.gov/pubmed/20812868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3570
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