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S-Nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration

Neurons are known to use large amounts of energy for their normal function and activity. In order to meet this demand, mitochondrial fission, fusion, and movement events (mitochondrial dynamics) control mitochondrial morphology, facilitating biogenesis and proper distribution of mitochondria within...

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Detalhes bibliográficos
Main Authors: Nakamura, Tomohiro, Cieplak, Piotr, Cho, Dong-Hyung, Godzik, Adam, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918703/
https://ncbi.nlm.nih.gov/pubmed/20447471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2010.04.007
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