Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the variant is located outside of a protein-coding region, the target genes driving tumorigenesis are not readily apparent. Two genes nearest to thi...

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Main Authors: Pomerantz, Mark M., Shrestha, Yashaswi, Flavin, Richard J., Regan, Meredith M., Penney, Kathryn L., Mucci, Lorelei A., Stampfer, Meir J., Hunter, David J., Chanock, Stephen J., Schafer, Eric J., Chan, Jennifer A., Tabernero, Josep, Baselga, José, Richardson, Andrea L., Loda, Massimo, Oh, William K., Kantoff, Philip W., Hahn, William C., Freedman, Matthew L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978684/
https://ncbi.nlm.nih.gov/pubmed/21085629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001204
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