Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the variant is located outside of a protein-coding region, the target genes driving tumorigenesis are not readily apparent. Two genes nearest to thi...

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Autors principals: Pomerantz, Mark M., Shrestha, Yashaswi, Flavin, Richard J., Regan, Meredith M., Penney, Kathryn L., Mucci, Lorelei A., Stampfer, Meir J., Hunter, David J., Chanock, Stephen J., Schafer, Eric J., Chan, Jennifer A., Tabernero, Josep, Baselga, José, Richardson, Andrea L., Loda, Massimo, Oh, William K., Kantoff, Philip W., Hahn, William C., Freedman, Matthew L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978684/
https://ncbi.nlm.nih.gov/pubmed/21085629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001204
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