Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the variant is located outside of a protein-coding region, the target genes driving tumorigenesis are not readily apparent. Two genes nearest to thi...

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Détails bibliographiques
Auteurs principaux: Pomerantz, Mark M., Shrestha, Yashaswi, Flavin, Richard J., Regan, Meredith M., Penney, Kathryn L., Mucci, Lorelei A., Stampfer, Meir J., Hunter, David J., Chanock, Stephen J., Schafer, Eric J., Chan, Jennifer A., Tabernero, Josep, Baselga, José, Richardson, Andrea L., Loda, Massimo, Oh, William K., Kantoff, Philip W., Hahn, William C., Freedman, Matthew L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978684/
https://ncbi.nlm.nih.gov/pubmed/21085629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001204
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