Investigation of the relationship between prostate cancer and MSMB and NCOA4 genetic variants and protein expression

Two genome-wide association studies (GWAS) identified the β-microseminoprotein (MSMB) promoter SNP, rs10993994:C>T, as significantly associated with prostate cancer (PC) risk. Follow-up studies demonstrate that the variant allele directly affects expression of the MSMB encoded protein, PSP94, and...

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Hauptverfasser: FitzGerald, Liesel M., Zhang, Xiaotun, Kolb, Suzanne, Kwon, Erika M., Liew, Ying Ching, Hurtado-Coll, Antonio, Knudsen, Beatrice S., Ostrander, Elaine A., Stanford, Janet L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532957/
https://ncbi.nlm.nih.gov/pubmed/22887727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22176
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