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Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen.

A bacterial expression system was used to produce simian virus 40 large tumor antigen (T antigen) in the absence of the extensive posttranslational modifications that occur in mammalian cells. Wild-type T antigen produced in bacteria retained a specific subset of the biochemical activities displayed...

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Bibliographische Detailangaben
Hauptverfasser: Mohr, I J, Gluzman, Y, Fairman, M P, Strauss, M, McVey, D, Stillman, B, Gerard, R D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC297867/
https://ncbi.nlm.nih.gov/pubmed/2549538
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