A deletion in the simian virus 40 large T antigen impairs lytic replication in monkey cells in vivo but enhances DNA replication in vitro: new complementation function of T antigen.

We describe a new complementation function within the simian virus 40 (SV40) A gene. This function is required for viral DNA replication and virus production in vivo but, surprisingly, does not affect any of the intrinsic enzymatic functions of T antigen directly required for in vitro DNA replicatio...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Maulbecker, C, Mohr, I, Gluzman, Y, Bartholomew, J, Botchan, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312627/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2195-2207.1992
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