TRE17/Ubiquitin-specific Protease 6 (USP6) Oncogene Translocated in Aneurysmal Bone Cyst Blocks Osteoblastic Maturation via an Autocrine Mechanism Involving Bone Morphogenetic Protein Dysregulation

Aneurysmal bone cyst (ABC) is a pediatric osseous tumor characterized by extensive destruction of the surrounding bone. The molecular mechanisms underlying its pathogenesis are completely unknown. Recent work showed that translocation of the TRE17/USP6 locus occurs in over 60% of ABC cases resulting...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Lau, Alan W., Pringle, Lashon M., Quick, Laura, Riquelme, Daisy N., Ye, Ying, Oliveira, Andre M., Chou, Margaret M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
Molecular Bases of Disease
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978639/
https://ncbi.nlm.nih.gov/pubmed/20864534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175133
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים