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Jak1-STAT3 signals are essential effectors of the USP6/TRE17 oncogene in tumorigenesis

Bone and soft tissue tumors are relatively poorly understood, hampering the development of effective therapies. Here we report a critical effector pathway for the ubiquitin-specific protease 6(USP6)/TRE17, which is overexpressed upon chromosome translation in various human tumors, including aneurysm...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Quick, Laura, Young, Robert, Henrich, Ian C., Wang, Xiaoke, Asmann, Yan W., Oliveira, Andre M., Chou, Margaret M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026615/
https://ncbi.nlm.nih.gov/pubmed/27440725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2391
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