TRE17/Ubiquitin-specific Protease 6 (USP6) Oncogene Translocated in Aneurysmal Bone Cyst Blocks Osteoblastic Maturation via an Autocrine Mechanism Involving Bone Morphogenetic Protein Dysregulation

Aneurysmal bone cyst (ABC) is a pediatric osseous tumor characterized by extensive destruction of the surrounding bone. The molecular mechanisms underlying its pathogenesis are completely unknown. Recent work showed that translocation of the TRE17/USP6 locus occurs in over 60% of ABC cases resulting...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lau, Alan W., Pringle, Lashon M., Quick, Laura, Riquelme, Daisy N., Ye, Ying, Oliveira, Andre M., Chou, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978639/
https://ncbi.nlm.nih.gov/pubmed/20864534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175133
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados