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Calcium Inhibits Paracellular Sodium Conductance through Claudin-2 by Competitive Binding
Claudins form paracellular pores at the tight junction in epithelial cells. Profound depletion of extracellular calcium is well known to cause loosening of the tight junction with loss of transepithelial resistance. However, moderate variations in calcium concentrations within the physiological rang...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978634/ https://ncbi.nlm.nih.gov/pubmed/20807759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146621 |
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