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The Alternative Pathway is critical for Pathogenic Complement Activation in Endotoxin- and Diet-induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice
BACKGROUND: The early components of the classical and lectin complement pathways have been shown to protect low-density lipoprotein receptor deficient mice (Ldlr(−/−)) from early atherogenesis. However, the role of the alternative pathway remained unknown and that was investigated in this study. MET...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978131/ https://ncbi.nlm.nih.gov/pubmed/20974996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.981365 |
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