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The Alternative Pathway is critical for Pathogenic Complement Activation in Endotoxin- and Diet-induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

BACKGROUND: The early components of the classical and lectin complement pathways have been shown to protect low-density lipoprotein receptor deficient mice (Ldlr(−/−)) from early atherogenesis. However, the role of the alternative pathway remained unknown and that was investigated in this study. MET...

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Bibliografische gegevens
Hoofdauteurs: Malik, Talat H., Cortini, Andrea, Carassiti, Daniele, Boyle, Joseph J, Haskard, Dorian O., Botto, Marina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978131/
https://ncbi.nlm.nih.gov/pubmed/20974996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.981365
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