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Immunoglobulin M is Required for Protection Against Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice
BACKGROUND: IgM natural antibodies bind oxidatively modified low-density lipoprotein (LDL) and apoptotic cells and have been implicated as important for protection from atherosclerosis. We have directly investigated the requirement for IgM by studying the effects of IgM deficiency in LDL receptor-de...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761224/ https://ncbi.nlm.nih.gov/pubmed/19620499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.868158 |
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