A Live Attenuated H7N7 Candidate Vaccine Virus Induces Neutralizing Antibody That Confers Protection from Challenge in Mice, Ferrets, and Monkeys

A live attenuated H7N7 candidate vaccine virus was generated by reverse genetics using the modified hemagglutinin (HA) and neuraminidase (NA) genes of highly pathogenic (HP) A/Netherlands/219/03 (NL/03) (H7N7) wild-type (wt) virus and the six internal protein genes of the cold-adapted (ca) A/Ann Arb...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Min, Ji-Young, Vogel, Leatrice, Matsuoka, Yumiko, Lu, Bin, Swayne, David, Jin, Hong, Kemble, George, Subbarao, Kanta
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2010
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977864/
https://ncbi.nlm.nih.gov/pubmed/20810733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01305-10
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