Development of a High-Yield Live Attenuated H7N9 Influenza Virus Vaccine That Provides Protection against Homologous and Heterologous H7 Wild-Type Viruses in Ferrets

Live attenuated H7N9 influenza vaccine viruses that possess the hemagglutinin (HA) and neuraminidase (NA) gene segments from the newly emerged wild-type (wt) A/Anhui/1/2013 (H7N9) and six internal protein gene segments from the cold-adapted influenza virus A/Ann Arbor/6/60 (AA ca) were generated by...

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Detalhes bibliográficos
Main Authors: Chen, Zhongying, Baz, Mariana, Lu, Janine, Paskel, Myeisha, Santos, Celia, Subbarao, Kanta, Jin, Hong, Matsuoka, Yumiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054345/
https://ncbi.nlm.nih.gov/pubmed/24719414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00100-14
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