African Green Monkeys Recapitulate the Clinical Experience with Replication of Live Attenuated Pandemic Influenza Virus Vaccine Candidates

Live attenuated cold-adapted (ca) H5N1, H7N3, H6N1, and H9N2 influenza vaccine viruses replicated in the respiratory tract of mice and ferrets, and 2 doses of vaccines were immunogenic and protected these animals from challenge infection with homologous and heterologous wild-type (wt) viruses of the...

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Hlavní autoři: Matsuoka, Yumiko, Suguitan, Amorsolo, Orandle, Marlene, Paskel, Myeisha, Boonnak, Kobporn, Gardner, Donald J., Feldmann, Friederike, Feldmann, Heinz, Marino, Michael, Jin, Hong, Kemble, George, Subbarao, Kanta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097805/
https://ncbi.nlm.nih.gov/pubmed/24807726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00425-14
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