Intracellular Distribution of NS1 Correlates with the Infectivity and Interferon Antagonism of an Avian Influenza Virus (H7N1)

Highly pathogenic avian influenza viruses of subtype H7N1 that emerged during an outbreak in 1999 and 2000 in Italy differ from their low-pathogenicity precursor viruses by changes in several genes, including three mutations in the NS1 protein. Two of them involve amino acid exchanges located within...

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Bibliographic Details
Main Authors: Keiner, Bjoern, Maenz, Benjamin, Wagner, Ralf, Cattoli, Giovanni, Capua, Ilaria, Klenk, Hans-Dieter
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977857/
https://ncbi.nlm.nih.gov/pubmed/20844052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01011-10
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