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Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.

The crystal structure of the complex of the anti-lysozyme HyHEL-10 Fab and hen egg white lysozyme has been determined to a nominal resolution of 3.0 A. The antigenic determinant (epitope) on the lysozyme is discontinuous, consisting of residues from four different regions of the linear sequence. It...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Padlan, E A, Silverton, E W, Sheriff, S, Cohen, G H, Smith-Gill, S J, Davies, D R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2762305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5938
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