High-resolution mapping of the HyHEL-10 epitope of chicken lysozyme by site-directed mutagenesis.

The complex formed between hen egg white lysozyme (HEL) and the monoclonal antibody HyHEL-10 Fab fragment has an interface composed of van der Waals interactions, hydrogen bonds, and a single ion pair. The antibody overlaps part of the active site cleft. Putative critical residues within the epitope...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kam-Morgan, L N, Smith-Gill, S J, Taylor, M G, Zhang, L, Wilson, A C, Kirsch, J F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46425/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7683415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.3958
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