High-resolution mapping of the HyHEL-10 epitope of chicken lysozyme by site-directed mutagenesis.

The complex formed between hen egg white lysozyme (HEL) and the monoclonal antibody HyHEL-10 Fab fragment has an interface composed of van der Waals interactions, hydrogen bonds, and a single ion pair. The antibody overlaps part of the active site cleft. Putative critical residues within the epitope...

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Main Authors: Kam-Morgan, L N, Smith-Gill, S J, Taylor, M G, Zhang, L, Wilson, A C, Kirsch, J F
格式: Artigo
語言:Inglês
出版: 1993
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC46425/
https://ncbi.nlm.nih.gov/pubmed/7683415
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