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Hydroxypropyl Methylcellulose Acetate Succinate: Potential Drug–Excipient Incompatibility
The stability of hydroxypropyl methylcellulose acetate succinate (HPMC-AS) and its potential incompatibility with active pharmaceutical ingredients (API) carrying hydroxyl group(s) were investigated in this research. HPMC-AS may undergo hydrolysis under harsh processing conditions with the generatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2977018/ https://ncbi.nlm.nih.gov/pubmed/18758966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9138-5 |
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