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Reactive Impurities in Excipients: Profiling, Identification and Mitigation of Drug–Excipient Incompatibility
Reactive impurities in pharmaceutical excipients could cause drug product instability, leading to decreased product performance, loss in potency, and/or formation of potentially toxic degradants. The levels of reactive impurities in excipients may vary between lots and vendors. Screening of excipien...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225520/ https://ncbi.nlm.nih.gov/pubmed/21948318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9677-z |
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