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Fabrication of Modified Release Tablet Formulation of Metoprolol Succinate using Hydroxypropyl Methylcellulose and Xanthan Gum
The present investigation was undertaken to fabricate modified release tablet of metoprolol succinate using hydroxypropyl methylcellulose (HPMC) and xanthan gum as a matrixing agent. A 3(2) full factorial design was employed for the optimization of formulation. The percentage drug released at a give...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663665/ https://ncbi.nlm.nih.gov/pubmed/19148762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9174-1 |
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