Llwytho...

The cationic amphiphile 3,4-bis(tetradecyloxy)benzylamine inhibits LPS signaling by competing with endotoxin for CD14 binding

The identification of the bacterial endotoxin receptors for innate immunity, most notably the Toll-like receptor 4 (TLR4), has sparked great interest in therapeutic manipulation of innate immune system. We have recently developed synthetic molecules that have been shown to inhibit TLR4 activation in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Piazza, Matteo, Calabrese, Valentina, Baruffa, Chiara, Gioannini, Theresa, Weiss, Jerrold, Peri, Francesco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976979/
https://ncbi.nlm.nih.gov/pubmed/20599783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.019
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