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Evidence of a specific interaction between new synthetic antisepsis agents and CD14

Synthetic molecules derived from natural sugars with a positively charged amino group or ammonium salt and two lipophilic chains have been shown to inhibit TLR4 activation in vitro and in vivo. In order to characterize the mechanism of action of this class of molecules, we investigated possible inte...

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Autors principals: Piazza, Matteo, Yu, Liping, Teghanemt, Athmane, Gioannini, Theresa, Weiss, Jerrold, Peri, Francesco
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802518/
https://ncbi.nlm.nih.gov/pubmed/19928913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901601b
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