Biophysical Mechanisms of Endotoxin Neutralization by Cationic Amphiphilic Peptides

Bacterial endotoxins (lipopolysaccharides (LPS)) are strong elicitors of the human immune system by interacting with serum and membrane proteins such as lipopolysaccharide-binding protein (LBP) and CD14 with high specificity. At LPS concentrations as low as 0.3 ng/ml, such interactions may lead to s...

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Détails bibliographiques
Auteurs principaux: Kaconis, Yani, Kowalski, Ina, Howe, Jörg, Brauser, Annemarie, Richter, Walter, Razquin-Olazarán, Iosu, Iñigo-Pestaña, Melania, Garidel, Patrick, Rössle, Manfred, Martinez de Tejada, Guillermo, Gutsmann, Thomas, Brandenburg, Klaus
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2011
Sujets:
Membrane
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117184/
https://ncbi.nlm.nih.gov/pubmed/21641310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.041
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