Biophysical Mechanisms of Endotoxin Neutralization by Cationic Amphiphilic Peptides

Bacterial endotoxins (lipopolysaccharides (LPS)) are strong elicitors of the human immune system by interacting with serum and membrane proteins such as lipopolysaccharide-binding protein (LBP) and CD14 with high specificity. At LPS concentrations as low as 0.3 ng/ml, such interactions may lead to s...

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Bibliografische gegevens
Hoofdauteurs: Kaconis, Yani, Kowalski, Ina, Howe, Jörg, Brauser, Annemarie, Richter, Walter, Razquin-Olazarán, Iosu, Iñigo-Pestaña, Melania, Garidel, Patrick, Rössle, Manfred, Martinez de Tejada, Guillermo, Gutsmann, Thomas, Brandenburg, Klaus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2011
Onderwerpen:
Membrane
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117184/
https://ncbi.nlm.nih.gov/pubmed/21641310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.041
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