Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families

BACKGROUND: Germline mutations in the DNA mismatch repair genes predispose to Lynch syndrome, thus conferring a high relative risk of colorectal and endometrial cancer. The MLH1, MSH2 and MSH6 mutational spectrum reported so far involves minor alterations scattered throughout their coding regions as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thodi, Georgia, Fostira, Florentia, Sandaltzopoulos, Raphael, Nasioulas, George, Grivas, Anastasios, Boukovinas, Ioannis, Mylonaki, Maria, Panopoulos, Christos, Magic, Mirjana Brankovic, Fountzilas, George, Yannoukakos, Drakoulis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976752/
https://ncbi.nlm.nih.gov/pubmed/20937110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-544
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg