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Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates
Activation of toll-like receptors (TLRs) on cells of the innate immune system initiates, amplifies, and directs the antigen-specific acquired immune response. Ligands that stimulate TLRs, therefore, represent potential immune adjuvants. In this study, a potent TLR7 agonist was conjugated to phosphol...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976567/ https://ncbi.nlm.nih.gov/pubmed/19445505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900054q |
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