Hare TRIM5α Restricts Divergent Retroviruses and Exhibits Significant Sequence Variation from Closely Related Lagomorpha TRIM5 Genes

TRIM5α proteins recruit and restrict incoming cytoplasmic retroviruses. Primate TRIM5α sequence diversity underlies species-specific restriction and is likely caused by selective pressure from ancient pathogenic infections. Here we show that TRIM5α from the European brown hare restricts diverse retr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fletcher, Adam J., Hué, Stéphane, Schaller, Torsten, Pillay, Deenan, Towers, Greg J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genetic Diversity and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976397/
https://ncbi.nlm.nih.gov/pubmed/20861252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01514-10
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker