The Chemokine Receptor CXCR2 Ligand KC (CXCL1) Mediates Neutrophil Recruitment and Is Critical for Development of Experimental Lyme Arthritis and Carditis

Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis. Following footpad inoculation of Borrelia burgdorferi, the agent of Lyme disease, expression of the CXCR2 ligand KC (CXCL1) is highly upregulated i...

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Main Authors: Ritzman, Anna M., Hughes-Hanks, Jennifer M., Blaho, Victoria A., Wax, Laura E., Mitchell, William J., Brown, Charles R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Host Response and Inflammation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976349/
https://ncbi.nlm.nih.gov/pubmed/20823213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00798-10
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