The Chemokine Receptor CXCR2 Ligand KC (CXCL1) Mediates Neutrophil Recruitment and Is Critical for Development of Experimental Lyme Arthritis and Carditis

Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis. Following footpad inoculation of Borrelia burgdorferi, the agent of Lyme disease, expression of the CXCR2 ligand KC (CXCL1) is highly upregulated i...

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Bibliografiske detaljer
Main Authors: Ritzman, Anna M., Hughes-Hanks, Jennifer M., Blaho, Victoria A., Wax, Laura E., Mitchell, William J., Brown, Charles R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976349/
https://ncbi.nlm.nih.gov/pubmed/20823213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00798-10
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