The Chemokine Receptor CXCR2 Ligand KC (CXCL1) Mediates Neutrophil Recruitment and Is Critical for Development of Experimental Lyme Arthritis and Carditis

Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis. Following footpad inoculation of Borrelia burgdorferi, the agent of Lyme disease, expression of the CXCR2 ligand KC (CXCL1) is highly upregulated i...

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Hlavní autoři: Ritzman, Anna M., Hughes-Hanks, Jennifer M., Blaho, Victoria A., Wax, Laura E., Mitchell, William J., Brown, Charles R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976349/
https://ncbi.nlm.nih.gov/pubmed/20823213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00798-10
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