Pharmacokinetics-Pharmacodynamics of a Respiratory Syncytial Virus Fusion Inhibitor in the Cotton Rat Model

Human respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in infants, young children, elderly persons, and severely immunocompromised patients. Effective postinfection treatments are not widely available, and currently there is no approved vaccine. TMC353121 is a...

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Autors principals: Rouan, Marie-Claude, Gevers, Tom, Roymans, Dirk, de Zwart, Loeckie, Nauwelaers, David, De Meulder, Marc, van Remoortere, Pieter, Vanstockem, Marc, Koul, Anil, Simmen, Kenny, Andries, Koen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976145/
https://ncbi.nlm.nih.gov/pubmed/20823290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00643-10
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