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Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen

The antiestrogenic drug tamoxifen is widely used in the treatment of estrogen receptor-α-positive breast cancer and substantially decreases recurrence and mortality rates. However, high interindividual variability in response is observed, calling for a personalized approach to tamoxifen treatment. T...

詳細記述

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書誌詳細
出版年:Clin Pharmacokinet
主要な著者: de Vries Schultink, Aurelia H. M., Zwart, Wilbert, Linn, Sabine C., Beijnen, Jos H., Huitema, Alwin D. R.
フォーマット: Artigo
言語:Inglês
出版事項: Springer International Publishing 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513218/
https://ncbi.nlm.nih.gov/pubmed/25940823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0273-3
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