Synthesis and Spectrum of the Neoglycoside ACHN-490

ACHN-490 is a neoglycoside, or “next-generation” aminoglycoside (AG), that has been identified as a potentially useful agent to combat drug-resistant bacteria emerging in hospitals and health care facilities around the world. A focused medicinal chemistry campaign produced a collection of over 400 s...

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Main Authors: Aggen, James B., Armstrong, Eliana S., Goldblum, Adam A., Dozzo, Paola, Linsell, Martin S., Gliedt, Micah J., Hildebrandt, Darin J., Feeney, Lee Ann, Kubo, Aya, Matias, Rowena D., Lopez, Sara, Gomez, Marcela, Wlasichuk, Kenneth B., Diokno, Raymond, Miller, George H., Moser, Heinz E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
Chemistry; Biosynthesis
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976124/
https://ncbi.nlm.nih.gov/pubmed/20805391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00572-10
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