ACHN-490, a Neoglycoside with Potent In Vitro Activity against Multidrug-Resistant Klebsiella pneumoniae Isolates

The in vitro activity of ACHN-490, a novel aminoglycoside (“neoglycoside”), was evaluated against 102 multidrug-resistant (MDR) Klebsiella pneumoniae strains, including a subset of 25 strains producing the KPC carbapenemase. MIC(50) values for gentamicin, tobramycin, and amikacin were 8 μg/ml, 32 μg...

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Detalhes bibliográficos
Main Authors: Endimiani, Andrea, Hujer, Kristine M., Hujer, Andrea M., Armstrong, Eliana S., Choudhary, Yuvraj, Aggen, James B., Bonomo, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764147/
https://ncbi.nlm.nih.gov/pubmed/19770287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00556-09
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