Synthesis and Spectrum of the Neoglycoside ACHN-490

ACHN-490 is a neoglycoside, or “next-generation” aminoglycoside (AG), that has been identified as a potentially useful agent to combat drug-resistant bacteria emerging in hospitals and health care facilities around the world. A focused medicinal chemistry campaign produced a collection of over 400 s...

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Autors principals: Aggen, James B., Armstrong, Eliana S., Goldblum, Adam A., Dozzo, Paola, Linsell, Martin S., Gliedt, Micah J., Hildebrandt, Darin J., Feeney, Lee Ann, Kubo, Aya, Matias, Rowena D., Lopez, Sara, Gomez, Marcela, Wlasichuk, Kenneth B., Diokno, Raymond, Miller, George H., Moser, Heinz E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Chemistry; Biosynthesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976124/
https://ncbi.nlm.nih.gov/pubmed/20805391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00572-10
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