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CHROMATOGRAPHIC STUDIES OF CHANGES IN BINDING OF SULFONYLUREA DRUGS TO HUMAN SERUM ALBUMIN DUE TO GLYCATION AND FATTY ACIDS
This report examines the use of high-performance affinity chromatography as a screening tool for studying the change in binding by sulfonylurea drugs to the protein human serum albumin (HSA) during diabetes. The effects of both the non-enzymatic glycation of HSA and the presence of fatty acids on th...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975824/ https://ncbi.nlm.nih.gov/pubmed/20974553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.033 |
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