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CHROMATOGRAPHIC ANALYSIS OF THE EFFECTS OF FATTY ACIDS AND GLYCATION ON BINDING BY PROBES FOR SUDLOW SITES I AND II TO HUMAN SERUM ALBUMIN

The primary endogenous ligands of human serum albumin (HSA) are non-esterified fatty acids, with 0.1–2 moles of fatty acids normally being bound to HSA. In type II diabetes, fatty acid levels in serum are often elevated, and the presence of high glucose results in an increase in the non-enzymatic gl...

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Veröffentlicht in:J Chromatogr B Analyt Technol Biomed Life Sci
Hauptverfasser: Anguizola, Jeanethe, Debolt, Erin, Suresh, D., Hage, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826644/
https://ncbi.nlm.nih.gov/pubmed/26468085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.09.041
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