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CHROMATOGRAPHIC ANALYSIS OF THE EFFECTS OF FATTY ACIDS AND GLYCATION ON BINDING BY PROBES FOR SUDLOW SITES I AND II TO HUMAN SERUM ALBUMIN
The primary endogenous ligands of human serum albumin (HSA) are non-esterified fatty acids, with 0.1–2 moles of fatty acids normally being bound to HSA. In type II diabetes, fatty acid levels in serum are often elevated, and the presence of high glucose results in an increase in the non-enzymatic gl...
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| Pubblicato in: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826644/ https://ncbi.nlm.nih.gov/pubmed/26468085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.09.041 |
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