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CHROMATOGRAPHIC STUDIES OF CHANGES IN BINDING OF SULFONYLUREA DRUGS TO HUMAN SERUM ALBUMIN DUE TO GLYCATION AND FATTY ACIDS

This report examines the use of high-performance affinity chromatography as a screening tool for studying the change in binding by sulfonylurea drugs to the protein human serum albumin (HSA) during diabetes. The effects of both the non-enzymatic glycation of HSA and the presence of fatty acids on th...

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Autors principals: Basiaga, Sara B. G., Hage, David S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975824/
https://ncbi.nlm.nih.gov/pubmed/20974553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.033
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