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The Structural Complexity of the Human BORIS Gene in Gametogenesis and Cancer
BACKGROUND: BORIS/CTCFL is a paralogue of CTCF, the major epigenetic regulator of vertebrate genomes. BORIS is normally expressed only in germ cells but is aberrantly activated in numerous cancers. While recent studies demonstrated that BORIS is a transcriptional activator of testis-specific genes,...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975627/ https://ncbi.nlm.nih.gov/pubmed/21079786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013872 |
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